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Animal studies demonstrated that the genitals and the brain acquire masculine or feminine traits at different stages of development in utero, setting up the potential for hormone fluctuations or other factors to put those organs on different tracks. A study that focused on cortical thickness, which tends to be slightly greater in women than in men, also yielded mixed results. A Dutch study similarly concluded that the overall brain volumes of transgender women dropped as a result of treatment, while those of transgender men increased, particularly in the hypothalamus Eur J Endocrinol , We have corrected the article to reflect the fact that Davis is focused on understanding the genetic contribution to gender identity, not specifically gender dysphoria.

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Transgender Candidate For Governor Wins Vermont Primary

Transgender rights have also become a mainstream political issue, and the idea that people should be referred to by the names and pronouns they find most fitting—whether or not these designations match those on their birth certificates, or align with the categories of male and female—is gaining acceptance. We spent a year asking the biggest names in Hollywood what makes a performance Oscar-worthy. Animal studies demonstrated that the genitals and the brain acquire masculine or feminine traits at different stages of development in utero, setting up the potential for hormone fluctuations or other factors to put those organs on different tracks. A Dutch study similarly concluded that the overall brain volumes of transgender women dropped as a result of treatment, while those of transgender men increased, particularly in the hypothalamus Eur J Endocrinol , Bakker and colleagues found that trans boys who had not been exposed to testosterone, but had had female pubertal hormones suppressed as well as cisgender boys, displayed less activation than cisgender girls in frontal brain areas when they performed the task. Other studies have pinpointed characteristics of the transgender brain that fall in between what is typical for either sex—results that proponents of the developmental mismatch hypothesis generally see as support for their idea.

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Trump signs new transgender military ban

In another study published in , Swaab and a coauthor examined the postmortem volume of the INAH3 subnucleus, an area of the hypothalamus previously linked to sexual orientation. In a study from the Netherlands Institute for Neuroscience, a comparison of the distribution of gray matter in 55 female-to-male and 38 male-to-female transgender adolescents with cisgender controls in the same age group found broad similarities in the hypothalami and the cerebellums of the transgender subjects and cisgender participants of the same natal sex. The team found that in some respects, such as the level of activation of a brain area called the right superior frontal gyrus, trans and cis women were similar, while cisgender men showed higher activity, possibly reflecting greater cognitive effort on the task. Functional similarities between transgender people and their cisgender counterparts were apparent in a study led by Julie Bakker of VU University Medical Center and the Netherlands Institute for Neuroscience in Amsterdam that examined neural activity during a spatial-reasoning task. But this finding did not hold true across the entire brain. In , for example, Georg Kranz , a neuroscientist at the Medical University of Vienna, used diffusion MRI data to investigate differences in white matter microstructure among trans- and cisgender subjects. The original version of this article incorrectly stated that Lea Davis is organizing a study to look for genetic variants linked to gender dysphoria.

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Description: The original version of this article incorrectly stated that Lea Davis is organizing a study to look for genetic variants linked to gender dysphoria. Functional similarities between transgender people and their cisgender counterparts were apparent in a study led by Julie Bakker of VU University Medical Center and the Netherlands Institute for Neuroscience in Amsterdam that examined neural activity during a spatial-reasoning task. For now, as is the case for many aspects of human experience, the neural mechanisms underlying gender remain largely mysterious. Every music video needs a leading lady, and these stars didn't come cheap. A study that focused on cortical thickness, which tends to be slightly greater in women than in men, also yielded mixed results. A Dutch study similarly concluded that the overall brain volumes of transgender women dropped as a result of treatment, while those of transgender men increased, particularly in the hypothalamus Eur J Endocrinol ,
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